Although minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) does not itself cause orthostatic hypotension , its administration to patients already receiving guanethidine can result in profound orthostatic effects. If at all possible, guanethidine should be discontinued well before minoxidil is begun. Where this is not possible, minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) therapy should be started in the hospital and the patient should remain institutionalized until severe orthostatic effects are no longer present or the patient has learned to avoid activities that provoke them.
The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases death, including euthanasia has been reported. Sudden death was sometimes preceded by vocalization or collapse.
E Maurin, I am very sorry to hear of your husband’s heart problem. He should continue to take the diuretics, which are essential if his heart condition is causing water retention. In this condition the excess water is in the blood, not the body’s tissues, so it is absolutely correct to prescribe Lasix or a similar product. Water pills can be safely used in this condition. They are not safe for ‘idiopathic oedema’ or water retention of unknown cause, where the excess water is in the tissues, not the blood. There is much that your husband can do to help himself. The most important supplements for congestive heart failure are coenzyme Q10, taurine and carnitine. He can take taurine and magnesium together by purchasing supplements of magnesium taurate. You can perhaps google where to buy these. I know you can get them from but I don’t know about other countries. Carnitine is cheapest if bought as a bulk powder rather than as capsules. You can mix it with juice. Coenzyme Q10 is the most expensive, and he will need to take at least 100 mg per day, in divided doses. I also recommend keeping up potassium levels by drinking unsalted tomato and beet juices and seasoning food with salt that contains potassium (some of the low-sodium brands are rich in potassium). Recent research shows that exercise is very beneficial for CHF, and you can google the recent research showing that beet juice helps make exercise easier for people with CHF.