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Heart disease in an otherwise healthy young athlete who is abusing anabolic steroids likely results from increased levels of low-density lipoprotein (LDL) and decreased levels of high-density lipoprotein (HDL).
Several studies suggest that anabolic steroid abuse in athletes increases LDL levels by > 20% and decreases HDL levels by 20% to 70%. These lipoprotein abnormalities have been shown to increase the risk for coronary artery disease three- to six-fold. Anabolic steroid abuse may cause cardiac ischemia by exaggerating oxygen demand at peak exercise, potentially precipitated by accelerated atherosclerosis from lipoprotein abnormalities over years of abuse.
Silver reviewed the adverse effects of anabolic steroids in a JAAOS article and reported that anabolic steroid use can lead to hypertension, changes in lipid profile, elevated liver enzymes, increased risk of tendon and muscle injury, testicular or uterine atrophy, depression, psychosis, and immunosuppression.
Achar et al. reviewed a total of 49 studies describing 1,467 athletes to investigate the cardiovascular effects of the anabolic steroid abuse. They found that anabolic steroid abuse was associated with elevated levels of LDL, low levels of HDL, elevated systolic and diastolic blood pressure, and left ventricular hypertrophy. They also noted that there were some small case studies describing fatal ventricular arrhythmias secondary to anabolic steroid abuse.
Answer 1: High density lipoprotein levels are decreased, not increased, in those abusing anabolic steroids. This decrease in HDL levels contributea to the development of heart disease in these otherwise healthy individuals.
Answer 2: Systolic and diastolic blood pressure are elevated, not decreased, after prolonged anabolic steroid use. This does not lead to heart disease in those who abuse anabolic steroids.
Answer 4: Alteration of myocardial conduction patterns (., ventricular arrhythmia) is not a cause of heart disease in anabolic steroid abusers. It is, however, a cause of sudden death in these individuals.
Answer 5: Anabolic steroids do not cause 'direct' endothelial damage to the coronary arteries.
Thirty-seven athletes represented Team GB in the swimming events. Selection followed the 2008 British Olympic Swimming Trials in Sheffield in April, with open water event swimmers selected after performance in the 2008 World Open Water Swimming Championships, in Seville , Spain. In winning six medals (two gold, two silver and two bronze) the team bettered the target of three medals set by UK Sport .  The most successful swimmer was Rebecca Adlington who won two gold medals. Her 400 m freestyle success was Britain's first Olympic swimming title since 1988 , and the first swimming gold by a British woman since 1960 . Her second gold, in the 800 m freestyle, meant she also equalled the best performance by a British woman, from any sport, at the summer Olympics and was the best swimming performance by a Briton at the Olympics for 100 years.