If long acting esters were used, then the existing drug from the heavy phase will have significant anabolic effectiveness for 2-3 weeks after injection, depending on dose, and thus no injectables would need to be used in those weeks. After that point, if Primobolan is not available, one might wish to continue with once-a-day dosing of orals or very low dose (100 mg/week) testosterone with use of anti-estrogens . A balance must be struck, however: there is a middle ground that we do not want to be in. There is a range where there is still some anabolic support yet there is fairly little inhibitory effect, but past this range, there still is not great anabolic effect, but there is substantial inhibition. One does not want to spend more time than necessary in this middle ground, but pass through it relatively quickly. Once in the light phase, the dose must remain low enough to allow recovery of natural hormone production to occur.
Having said that, the results so far of the studies on LDN have been really encouraging, and they’ve been primarily on cancer, multiple sclerosis, Crohn’s disease, fibromyalgia, and autism. It’s especially effective for Crohn’s with over a 70% remission rate and even complete mucosal healing as evidenced by colonoscopy in some cases. If you know about Crohn’s disease and how nasty it can be and how difficult to treat and how poor the success rates are of the typical treatments, that’s a pretty remarkable statistic, over 70% remission rate with mucosal healing, especially when you consider the fact that there were not documented side effects of LDN in that study compared to placebo.